Facultad de Ciencias de la Salud Eugenio Espejo

Director

FELIX GALLEGOS, CAMILO EDGAR VINICIO

Parent Organisation

Universidad UTE

Country

City

Quito

Now showing 1 - 10 of 337

Some of the metrics are blocked by your
consent settings
Disparidades rural-urbanas en la mortalidad materna en Ecuador: Un análisis desde una perspectiva de género (2019–2021)
(2025)
SÁNCHEZ VERDUGA, SAMI GABRIELA
;
IZURIETA GUEVARA, MÓNICA GIOCONDA
;
LALANGUI VIVANCO, KARINA DEL ROCÍO
;
QUENTIN, EMMANUELLE
;
NÚÑEZ VÁSQUEZ, CRISTINA ELIZABETH
La mortalidad materna es un indicador sensible de desigualdad en los sistemas de salud. En Ecuador persisten marcadas brechas sociales entre zonas rurales y urbanas, acentuadas por factores estructurales como el territorio, la etnicidad y el género. Este estudio analiza las disparidades rural-urbanas en la mortalidad materna entre 2019 y 2021 desde un enfoque interseccional y de derechos humanos. Se utilizaron datos oficiales del Ministerio de Salud Pública e INEC, así como herramientas de análisis estadístico y georreferenciación. Los hallazgos evidencian razones de mortalidad materna más elevadas en el área rural, provincias fronterizas y especialmente entre mujeres racializadas y de edades avanzadas. Se concluye que los sistemas de salud deben contemplar recursos e inversión en estas áreas y grupos, así como las operaciones logísticas y de comunicación necesarias para una oportuna atención prenatal.
Some of the metrics are blocked by your
consent settings
Microbiota dynamics preceding bariatric surgery as obesity treatment: a comprehensive review
(Frontiers Media SA, 2024-04-03)
ZAMBRANO ESPINOSA, ANA KARINA
;
Elius Paz-Cruz
;
Viviana A. Ruiz-Pozo
;
Santiago Cadena-Ullauri
;
Rafael Tamayo-Trujillo
The review present data on the intricate relationship between bariatric surgery, gut microbiota, and metabolic health in obesity treatment. Bariatric surgery, is recognized as an effective intervention for managing morbid obesity, including various techniques with distinct mechanisms of action, efficacy, and safety profiles including Roux-en-Y Gastric Bypass (RYGB), Sleeve Gastrectomy (SG), Laparoscopic Adjustable Gastric Banding (LAGB), and Biliopancreatic Diversion (BPD). RYGB and SG are the most prevalent procedures globally, inducing gut microbiota changes that influence microbial diversity and abundance. Post-surgery, alterations in bacterial communities occur, such as the increased of <jats:italic>Escherichia coli inversely correlated with fat mass and leptin levels. During digestion, microbiota produce physiologically active compounds like bile acids (Bas) and short-chain fatty acids (SCFAs). SCFAs, derived by microbial fermentation, influence appetite, energy metabolism, and obesity-related pathways. Bas, altered by surgery, modulate glucose metabolism and insulin sensitivity. Furthermore, SG and RYGB enhance incretin secretion, particularly glucagon-like peptide 1 (GLP-1). Therefore, understanding microbiota changes after bariatric surgery could be crucial for predicting metabolic outcomes and developing targeted interventions for obesity management.
Scopus© Citations 18
Some of the metrics are blocked by your
consent settings
Late complication due to rhinoplasty with non-absorbable tension threads: A case report
(Elsevier BV, 2025-07)
Yekaterina Altuna-Roshkova
;
VILLARREAL ORTIZ, GHISLAYNE DANIELA
;
Diana Villarroel-Mosquera
;
Jaime Angamarca-Iguago
;
Juan Marcos Parise-Vasco
Introduction: Rhinomodeling is a minimally invasive aesthetic procedure that offers quick recovery and lower costs compared to surgical rhinoplasty. However, the use of non-absorbable tension threads can lead to late complications requiring surgical intervention. Case presentation: A 27-year-old female patient underwent rhinomodeling with non-absorbable tension threads ten years ago. She presented with nasal asymmetry, respiratory difficulty, and a foreign body sensation in the left nasal cavity. Clinical examination revealed left-sided laterorhinia, asymmetric nasal cavities, and a protruding tension thread. An open rhinoseptoplasty was performed, revealing thread extrusion, granuloma formation, and partial rupture of the right alar cartilage. The thread was removed, and structural correction was performed with septoplasty and cartilage grafting. Discussion: Unlike absorbable threads, which degrade within months, non-absorbable threads can cause late complications requiring surgical removal. Conclusion: This case highlights a late complication of rhinomodeling, previously described but underreported, requiring surgical intervention ten years later. Open rhinoseptoplasty successfully restored nasal function and aesthetics, emphasizing the importance of long-term follow-up and professional expertise.
Some of the metrics are blocked by your
consent settings
Innovation and bioethics in surgery: Redefining boundaries for a safe and human-centered future
(Medwave Estudios Limitada, 2025-03-06)
Evelyn Frias-Toral
;
Alex Enrique Vásconez García
;
Melannie Toral-Noristz
;
Martín Campuzano-Donoso
;
ZAMBRANO ESPINOSA, ANA KARINA
Since surgery is a complex procedure due to multiple factors, it is more difficult to rigorously evaluate innovative processes in this field than clinical trials of new drugs. Being able to carry out an adequate study design with all its corresponding implications, achieving high-quality standards for these studies, ensuring respect for patients' rights, and verifying that their principles of beneficence, minimization of the risk of harm, justice and autonomy are a challenge for many researchers and professionals involved in the surgical process. Hence, it is advantageous to have guides that guarantee the methodological quality of research on innovative surgical procedures and that these guides include the ethical aspects involved in each of their stages. This review aims to make a historical overview of what has been published on the ethical approach to surgical innovation. In addition, the ethical aspects of the stages of the IDEAL framework for surgical innovation will be explained.
Scopus© Citations 1
Some of the metrics are blocked by your
consent settings
High—throughput and automated screening for COVID-19
(Frontiers Media SA, 2022-09-15)
Nestor Jonguitud-Borrego
;
Koray Malcı
;
Mihir Anand
;
Erikan Baluku
;
Calum Webb
<jats:p>The COVID-19 pandemic has become a global challenge for the healthcare systems of many countries with 6 million people having lost their lives and 530 million more having tested positive for the virus. Robust testing and a comprehensive track and trace process for positive patients are essential for effective pandemic control, leading to high demand for diagnostic testing. In order to comply with demand and increase testing capacity worldwide, automated workflows have come into prominence as they enable high-throughput screening, faster processing, exclusion of human error, repeatability, reproducibility and diagnostic precision. The gold standard for COVID-19 testing so far has been RT-qPCR, however, different SARS-CoV-2 testing methods have been developed to be combined with high throughput testing to improve diagnosis. Case studies in China, Spain and the United Kingdom have been reviewed and automation has been proven to be promising for mass testing. Free and Open Source scientific and medical Hardware (FOSH) plays a vital role in this matter but there are some challenges to be overcome before automation can be fully implemented. This review discusses the importance of automated high-throughput testing, the different equipment available, the bottlenecks of its implementation and key selected case studies that due to their high effectiveness are already in use in hospitals and research centres.</jats:p>
Scopus© Citations 16
Some of the metrics are blocked by your
consent settings
Colchicine and the combination of rivaroxaban and aspirin in patients hospitalised with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial
(Elsevier BV, 2022-12)
John W Eikelboom
;
Sanjit S Jolly
;
Emilie P Belley-Cote
;
Richard P Whitlock
;
Sumathy Rangarajan
Scopus© Citations 25
Some of the metrics are blocked by your
consent settings
Molecular analysis of ancestry informative markers (AIMs-INDELs) in a high altitude Ecuadorian mestizo population affected with breast cancer
(Elsevier BV, 2017-12)
A. López-Cortés
;
G. Echeverría-Garcés
;
G. Burgos
;
ZAMBRANO ESPINOSA, ANA KARINA
;
A. Cabrera-Andrade
Scopus© Citations 2
Some of the metrics are blocked by your
consent settings
Effects of true-to-life PET nanoplastics using primary human nasal epithelial cells
(Elsevier BV, 2023-06)
Balasubramanyam Annangi
;
Aliro Villacorta
;
VELA ROMERO, LOURDES AMPARO
;
Alireza Tavakolpournegari
;
Ricard Marcos
Scopus© Citations 57
Some of the metrics are blocked by your
consent settings
The spatio-temporal dynamics of infant mortality in Ecuador from 2010 to 2019
(Springer Science and Business Media LLC, 2022-10-01)
Karina Lalangui
;
Karina Rivadeneira Maya
;
Christian Sánchez-Carrillo
;
Gersain Sosa Cortéz
;
QUENTIN, EMMANUELLE
<jats:title>Abstract</jats:title><jats:p>The infant mortality rate (IMR) is still a key indicator in a middle-income country such as Ecuador where a slightly increase up to 11.75 deaths per thousand life births has been observed in 2019. The purpose of this study is to propose and apply a prioritization method that combines clusters detection (Local Indicators of Spatial Association, LISA) and a monotonic statistic depicting time trend over 10 years (Mann–Kendall) at municipal level. Annual national databases (2010 to 2019) of live births and general deaths are downloaded from National Institute of Statistics and Censuses (INEC). The results allow identifying a slight increase in the IMR at the national level from 9.85‰ in 2014 to 11.75‰ in 2019, neonatal mortality accounted for 60% of the IMR in the last year. The LISA analysis allowed observing that the high-high clusters are mainly concentrated in the central highlands. At the local level, Piñas, Cuenca, Ibarra and Babahoyo registered the highest growth trends (0.7,1). The combination of techniques made it possible to identify eight priority counties, half of them pertaining to the highlands region, two to the coastal region and two to the Amazon region. To keep infant mortality at a low level is necessary to prioritize critical areas where public allocation of funds should be concentrated and formulation of policies.</jats:p>
Scopus© Citations 3
Some of the metrics are blocked by your
consent settings
Obesity and Obesity-Related Thyroid Dysfunction: Any Potential Role for the Very Low-Calorie Ketogenic Diet (VLCKD)?
(Springer Science and Business Media LLC, 2024-03-25)
Sebastián Pablo Chapela
;
Alison Simancas-Racines
;
Florencia Ceriani
;
Andrés Luciano Nicolas Martinuzzi
;
María Paula Russo
This review aims to explore in-depth the different aspects of the association between very low-calorie ketogenic diet (VLCKD), obesity and obesity-related thyroid dysfunction Recent Findings The VLCKD, proposed as a non-pharmacological strategy for the management of certain chronic diseases, is becoming increasingly popular worldwide. Initially used to treat epilepsy, it has been shown to be effective in controlling body weight gain and addressing various pathophysiological conditions. Research has shown that a low-calorie, high-fat diet can affect thyroid hormone levels. Weight loss can also influence thyroid hormone levels. Studies have suggested that long-term use of VLCKD for refractory epilepsy may be related to the development of hypothyroidism, with an effect seen in various populations. In particular, women with obesity following VLCKD tend to have reduced T3 levels. Summary We propose further research to unravel the underlying mechanisms linking VLCKD to obesity and obesity-related thyroid dysfunction
Scopus© Citations 18

Facultad de Ciencias de la Salud Eugenio Espejo

Filters

Settings

Sort By

Results per page