ZÚÑIGA MIRANDA, JOHANA JANINA
Preferred name
ZÚÑIGA MIRANDA, JOHANA JANINA
Main Affiliation
CENBIO - Centro de Investigación Biomédica
Web Site
ORCID
0000-0001-9037-9306
Scopus Author ID
57822779800
27 results
Now showing 1 - 10 of 27
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Item type:Publication, Crystal Structure, Hirshfeld Surface Analysis, and Biological Activities of Schiff-Base Derivatives of 4-Aminoantipyrine(American Chemical Society (ACS), 2023-10-31); Scopus© Citations 32 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Fluorinated Chromone
Derivatives: Synthesis, Theoretical
Study, and Evaluation of Their Biological Potential(American Chemical Society (ACS), 2026-07-27); ; - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Green Synthesis of Silver Oxide Nanoparticles from Mauritia flexuosa Fruit Extract: Characterization and Bioactivity Assessment(MDPI AG, 2024-11-22); Scopus© Citations 15 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Evaluation of Biological Activity of Natural Compounds: Current Trends and Methods(MDPI AG, 2022-07-13); Scopus© Citations 150 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Iron Oxide Nanoparticles: Green Synthesis and Their Antimicrobial Activity(MDPI AG, 2023-11-08); ; Carlos Barba-Ostria<jats:p>The rise of antimicrobial resistance caused by inappropriate use of these agents in various settings has become a global health threat. Nanotechnology offers the potential for the synthesis of nanoparticles (NPs) with antimicrobial activity, such as iron oxide nanoparticles (IONPs). The use of IONPs is a promising way to overcome antimicrobial resistance or pathogenicity because of their ability to interact with several biological molecules and to inhibit microbial growth. In this review, we outline the pivotal findings over the past decade concerning methods for the green synthesis of IONPs using bacteria, fungi, plants, and organic waste. Subsequently, we delve into the primary challenges encountered in green synthesis utilizing diverse organisms and organic materials. Furthermore, we compile the most common methods employed for the characterization of these IONPs. To conclude, we highlight the applications of these IONPs as promising antibacterial, antifungal, antiparasitic, and antiviral agents.</jats:p>Scopus© Citations 153 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Functional Evaluation, Antioxidant, Antimicrobial, Antibiofilm, and Haemolytic Capacity of Calathea lutea (Bijao) and Calathea inocephala (Shutupipanga) Leaves(MDPI AG, 2026-02-24); Scopus© Citations 3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Low-Temperature xTB–MD–DFT Screening of Functionalized Oxide Surface-Patch Models (TiO2, ZnO, CeO2) for Hydrocarbon Association and Microbial-Proxy Perturbation Assessment in Cold Bioremediation(MDPI AG, 2026-07-01); - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Bioactive Composition of Tropical Flowers and Their Antioxidant and Antimicrobial Properties(MDPI AG, 2024-11-24); This study evaluated tropical flower petals’ bioactive compounds and antioxidant and antimicrobial properties. The physicochemical characteristics, carotenoids, phenolics, anthocyanins, organic acids, and antioxidant activity of 67 flowers were analyzed. In addition, the antimicrobial activity against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus mutans, Candida albicans, and Candida tropicalis of 35 species was determined. A 2 × 3 experimental design was used for the extraction of carotenoids and phenolics, including solvents and ultrasonic agitation times. The mixture of methanol–acetone–dichloromethane (1:1:2) and acetone–methanol (2:1) resulted in the highest concentration of carotenoids, while acidified 80% methanol favoured phenolic extraction. Renealmia alpinia was extremely rich in carotenoids (292.5 mg β-carotene/g DW), Pleroma heteromallum in anthocyanins (7.35 mg C-3-gl/g DW), while a high content of citric acid was found in Hibiscus rosa-sinensis (17,819 mg/100 g DW). On the other hand, Thibaudia floribunda showed the highest antioxidant activity (7.8 mmol Trolox equivalent/g DW). The main phenolics were m-coumaric acid in Acalypha poiretii (12,044 mg/100 g DW), 4-hydroxybenzoic acid in Brugmansia arborea (10,729 mg/100 g DW), and kaempferol in Dahlia pinnata (8236 mg/100 g DW). The extract of Acalypha poiretii, Brownea macrophylla, and Cavendishia nobilis showed antibacterial activity, while the extract of Pleroma heteromallum was the only one active against Candida albicans. These findings highlight the potential health benefits from certain tropical flowers.Scopus© Citations 13 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Exploring the Multifaceted Biological Activities of Anthocyanins Isolated from Two Andean Berries(MDPI AG, 2024-08-21); ; Natural pigments extracted from plant species are used in foods, cosmetics, and pharmaceuticals. This study evaluates the comprehensive biological activities of anthocyanins isolated from Andean blueberry (Vaccinium floribundum Kunth) and Andean blackberry (Rubus glaucus Benth), focusing on their antimicrobial, antioxidant, antitumoral, anti-inflammatory, and hemolytic properties. Chemical characterization revealed significant anthocyanin content with complex mass spectrometric profiles indicating diverse glycosylation patterns that may influence their bioactivity. The antimicrobial assays showed that the extracts were particularly effective against Gram-positive bacteria, with minimal inhibitory concentrations (MICs) as low as 1 mg/mL for Rubus glaucus, indicating strong potential for therapeutic use. The antioxidant capacity of the berries was substantial, albeit slightly lower than that of ascorbic acid. The extracts also exhibited notable antitumoral activity in various cancer cell lines, showing promise as adjunctive or preventive treatments. The anti-inflammatory effects were confirmed by inhibiting nitric oxide production in macrophage cells, highlighting their potential in managing inflammatory diseases. In terms of hemolytic activity, Rubus glaucus exhibited dose-dependent effects, potentially attributable to anthocyanins and phenolics, while Vaccinium floribundum demonstrated no significant hemolytic activity, underscoring its safety. These findings suggest that anthocyanins from Andean berries possess potent biological activities, which could be leveraged for health benefits in pharmaceutical and nutraceutical applications. Further studies are needed to isolate specific bioactive compounds and investigate their synergistic effects in clinical and real-world contexts.Scopus© Citations 13 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Functional, Antioxidant, Antibacterial, and Antifungal Activity of Edible Flowers(MDPI AG, 2024-10-25)Scopus© Citations 22
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