Facultad de Medicina Veterinaria y Agronomía
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Item type:Publication, Diagnóstico y tratamiento de shunt portosistémico hepático.(Revista Científica Multidisciplinar G-ner@ndo, 2025-01-22) ;Marco Enrique Almeida Feijo; ;Jean Pierre Cueva Loayza ;Valeska Annabelle GarcíaWilliam Paul Abata MurilloEl shunt portosistémico (SPS) es una anomalía vascular que afecta a caninos, permitiendo que la sangre eluda el hígado y entre directamente en la circulación sistémica, lo que resulta en acumulación de toxinas y complicaciones graves como encefalopatía hepática. Este caso describe el diagnóstico y tratamiento de una perra Shih Tzu con SPS extrahepático, pancreatitis severa y litiasis renal. Se utilizaron herramientas diagnósticas como ecografía Doppler y análisis bioquímicos para confirmar las patologías. El tratamiento incluyó cirugía correctiva del SPS, fluidoterapia, transfusión, antibióticos y protectores hepáticos, logrando una estabilización clínica significativa. Este reporte resalta la importancia del diagnóstico temprano y el manejo integral en pacientes con enfermedades hepáticas complejas y comorbilidades. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Salmonella enterica Serovar Infantis KPC-2 Producer: First Isolate Reported in Ecuador(Mary Ann Liebert Inc, 2024-12-01); ;Viviana Albán ;Carolina Satán ;Hidaleisy QuintanaWladimir EnríquezAntimicrobial resistance is currently considered a public health threat. Carbapenems are antimicrobials for hospital use, and Enterobacterales resistant to these β-lactams have spread alarmingly in recent years, especially those that cause health care-associated infections. The blaKPC gene is considered one of the most important genetic determinants disseminated by plasmids, promoting horizontal gene transfer. This study describes, for the first time in Ecuador, and worldwide, the presence of a blaKPC-2 gene in an isolate of Salmonella enterica serovar Infantis from a clinical sample. Through whole-genome sequencing, we characterized the genetic determinants of antimicrobial resistance in this Salmonella ST-32 strain. Our results showed the presence of several resistance genes, including blaCTX-M-65, and a conjugative plasmid Kpn-WC17-007-03 that may be responsible for the horizontal transference of these resistance mechanisms.Scopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Demographic collapse threatens the long-term persistence of Andean condors in the northern Andes(Elsevier BV, 2023-09) ;Julián Padró ;Félix Hernán Vargas ;Sergio A. Lambertucci ;Paula L. PerrigJonathan N. PauliScopus© Citations 6 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Defining Spatial Conservation Priorities for the Andean Condor (Vultur gryphus)(The Raptor Research Foundation, Inc., 2022-02-28) ;Robert B. Wallace ;Ariel Reinaga ;Natalia Piland ;Renzo PianaF. Hernán VargasScopus© Citations 9 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Genomic characterization of a WHO critical priority isolate Enterobacter kobei ST2070 harboring OXA-10, KPC-2, and CTX-M-12 recovered from a water irrigation channel in Ecuador(Elsevier BV, 2024-03) ;Joselyn Corrales-Martínez ;Katherine Jaramillo ;Daniel A. Tadesse ;Carolina SatánThe discharge of untreated or partially treated wastewater can have detrimental impacts on the quality of water bodies, posing a significant threat to public health and the environment. In Ecuador, previous research indicates a high prevalence of antimicrobial resistant (AMR) bacteria in surface waters affected by human activities, including irrigation channels. In this study, we analyzed sediment samples collected from an irrigation channel utilized for agricultural purposes in northern Ecuador, using microbiological techniques and whole-genome sequencing (WGS). Our investigation revealed the first documented occurrence of E. kobei in Ecuador and the initial report of environmental E. kobei ST2070. Furthermore, we identified the coexistence of OXA-10-type class D β-lactamase and KPC-2-type class A β-lactamase in the E. kobei isolate (UTA41), representing the first report of such a phenomenon in this species. Additionally, we detected various antibiotic resistance genes in the E. kobei UTA41 isolate, including blaCTX-M-12, fosA, aac(6′)-lb, sul2, msr(E), and mph(A), as well as virulence genes such as bacterial efflux pump and siderophore biosynthesis genes. We also identified two intact prophage regions (Entero_186 and Klebsi_phiKO2) in the isolate. Our study presents the first evidence of E. kobei isolate containing two carbapenemase-encoding genes in environmental samples from Latin America. This finding indicates the potential spread of critical-priority bacteria in water samples originating from anthropogenic sources, such as urban wastewater discharges and livestock facilities.Scopus© Citations 7 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, An intersectionality perspective on tuberculosis: social determinants affecting tuberculosis mortality rate in Ecuador(Frontiers Media SA, 2025-10-24) ;Ángel Sebastián Rodríguez-Pazmiño ;Darwin Paredes-Núñez; ; Solon Alberto OrlandoThe Intersectionality approach to studying tuberculosis (TB) is a complex one. While historical data and indicators consistently suggest a positive correlation between social determinants, such as poverty, and TB mortality, the strength of this association varies across different regions and countries. Overcrowding and population density are also recognized as risk factors for TB transmission. Methods In this study, we conducted a descriptive and observational statistical analysis of TB mortality in Ecuador using the most recent public data from 2010. We examined the association between TB mortality and poverty, as well as territorial distribution, population density, and overcrowding. Results Our univariate analysis results indicate that the rural parishes or canton capitals in the first quintile of poverty (Q1) had the highest average mortality rates (14.23 per 100,000 inhabitants). Furthermore, the average TB mortality ratio was substantially higher in rural areas compared to urban ones (12.72 vs. 7.5 per 100,000 inhabitants). Interestingly, zones with the highest population density had a significantly lower average TB mortality ratio than those with the lowest density (4.82 vs. 15.19 per 100,000 inhabitants). Likewise, overcrowding analysis reveals a significant difference between the group with the highest level (O1) vs. the lowest one (O5; 14.3 vs. 6.8 per 100,000 inhabitants). On the other hand, a multivariate linear regression model agrees that three of the four independent variables evaluated had statistically significant associations with tuberculosis mortality rate. The percentage of poverty, living in a rural area, and population density were significant predictors of higher mortality. In contrast, the level of overcrowding, as determined by multivariate analysis, did not show a significant association when the other independent variables were taken into account. Discussion These findings reinforce the strong link between TB mortality and poverty, rurality, a discreet relationship with overcrowding, and an inverse relationship with population density in the Ecuadorian context, highlighting the need for targeted public health interventions in rural underserved communities. Future research should explore how changes in socioeconomic conditions and healthcare access have influenced TB incidence.Scopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Preoperative Nutrition in Bariatric Surgery: A Narrative Review on Enhancing Surgical Success and Patient Outcomes(MDPI AG, 2025-02-02) ;SIMANCAS RACINES, DANIEL ALEJANDRO ;Evelyn Frias Toral ;Martín Campuzano-Donoso; Raynier Zambrano-VillacresBariatric surgery has become the preferred treatment for individuals with morbid obesity. Nutrition is key in optimizing surgical outcomes by reducing risks and enhancing recovery. Preoperative strategies, such as reducing body fat, decreasing liver size, and improving metabolic profiles, have been shown to facilitate safer surgical procedures with fewer complications. This narrative review aims to provide an analysis of the fundamental role of preoperative nutritional management in improving bariatric surgery outcomes, emphasizing the importance of addressing specific nutritional challenges to enhance surgical safety, recovery, and overall health. Preoperative nutritional interventions focus on correcting comorbidities and nutritional deficiencies, particularly hypovitaminosis and micronutrient imbalances, through a multidisciplinary approach involving nutritionists and other healthcare professionals. These interventions not only prepare patients for the physiological demands of surgery but also initiate a period of adaptation to new dietary habits, aiming to improve long-term compliance and mitigate risks such as postoperative weight regain and dumping syndrome. Adopting dietary changes, such as very low-calorie or ketogenic diets 6–12 weeks before surgery, enhances adherence to postoperative restrictions and overall surgical success. Future research should focus on developing comprehensive guidelines for preoperative nutritional care to improve patient outcomes globally.Scopus© Citations 24 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Microplásticos en ambientes urbanos: el perro como bioindicador de exposición y riesgo gastrointestinal humano(Instituto Nacional de Salud (Colombia), 2026-08-20); ; ;Sailema-Rosado, Gianina ;Sangache-Guamán, AllissonBustos-Chávez, NataliaScopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Research note: High-resolution detection of Salmonella serovar diversity in broilers from Ecuador using CRISPR-SeroSeq(Elsevier BV, 2026-04) ;Christian Vinueza-Burgos ;José L. Medina-Santana ;Sofía de Janon; David Ayala-VelasteguiSalmonella enterica is a major foodborne pathogen associated with poultry, representing a critical challenge for food safety worldwide. Accurate identification of serovar diversity is essential for designing control strategies; however, conventional culture-based methods often underestimate this complexity. In this study, we report the first application of CRISPR-SeroSeq in Ecuador to characterize Salmonella serovar diversity in commercial broilers. A total of 76 flocks (one hose of one farm in different cycles) originated across 19 broiler farms were sampled. All flocks belonged to an integrated poultry company. From all samples, 77.6% tested positive for Salmonella. CRISPR-SeroSeq analysis revealed a clear dominance of serovar Infantis, even within mixed populations. Importantly, serovars of significant public health concern, including Enteritidis and Typhimurium, were detected at low frequencies that would likely be missed by conventional methods. These findings highlight the utility of high-resolution serotyping approaches, providing valuable insights for targeted interventions to improve poultry production biosecurity and food safety. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Specialized Feed-Additive Blends of Short- and Medium-Chain Fatty Acids Improve Sow and Pig Performance During Nursery and Post-Weaning Phase(MDPI AG, 2024-12-20); ; ;Sandra van Kuijk ;José F. PérezDavid Solà-OriolThe present study investigates the impact of supplementing diets with a synergistic blend of short- and medium-chain fatty acids (SCFAs-MCFAs) during the peripartum and lactation phases on early microbial colonization and the subsequent growth performance of newborn pigs. The experiment involved 72 sows and their litters, with a follow-up on 528 weaned pigs. Sows were fed either a control diet or a diet supplemented with SCFAs-MCFAs and the pigs were monitored for their growth performance and microbial populations. Subsequently, selected weaned pigs were allotted to an SCFAs-MCFAs diet according to the maternal diet. Results showed that SCFAs-MCFAs supplementation led to reduced backfat loss in sows and improved pig weight and uniformity at weaning (p < 0.05). Additionally, suckling pigs exhibited significant shifts in gut microbiota, including increased lactic acid bacteria and reduced Streptococcus suis populations (p < 0.05). Although there was no influence of maternal diet on pig growth after weaning, there was a modulation on bacterial populations at 7 and 35 days post-weaning. Pigs fed SCFAs-MCFAs demonstrated improved feed efficiency with notable reductions in E. coli and Streptococcus suis counts. The findings suggest that maternal dietary supplementation with SCFAs-MCFAs can positively influence both sow and pig performance, offering a potential strategy to enhance productivity and health in the commercial swine production.Scopus© Citations 5
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