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Corrigendum to Epidemiological Profile of Oral Health Conditions in Ecuador: A Retrospective Study From 2016 to 2022
(Elsevier BV, 2026-02)
W.B. Willy Bustillos Torrez
;
C.M. Cecilia Belén Molina Jaramillo
;
C.H. Christian Patricio Hernández Carrera
;
A.G. Ana Patricia Gutiérrez
;
D.L. Darwin Vicente Luna Chonata
The Global Action Plan on Oral Health 2023-2030 is reaffirmed, promoting prevention, equitable access, and affordability of essential oral healthcare, aligned with universal health coverage and addressing social and commercial determinants of oral health. The plan aims for resilient health systems based on primary healthcare (PHC). Objective The objective of this study is to determine the frequency and distribution of the main oral pathologies treated in the establishments of the Ministry of Public Health of Ecuador between 2016 and 2022. Methodology This study employs a retrospective methodology, utilizing a database provided by the Ministry of Public Health of Ecuador of the RDACAA and PRAS applications, treated in the Qview program, and presented in Microsoft Excel 2019. The Ministry of Public Health of Ecuador uses the ICD-10 code for the coding of diagnoses, considering age, sex, ethnic self-identification, and priority groups. Results The results show that dentin caries (K02.1) is the most frequent pathology, followed by acute gingivitis (K05.0) and deposits on teeth (K03.6). Conclusions This study provides crucial information at a national level and proposes to be a pioneer in the planning and execution of oral health policies in Ecuador, suggesting a reformulation of the National Oral Health Plan.
NARVÁEZ BENAVIDES , MARÍA FERNANDA
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Experimental assessment of acid gas energy recovery potential in refinery operations
(Springer Science and Business Media LLC, 2026-03-17)
Murillo-Calderon, Israel Alejandro
CENTENO PILAGUANO, RUTH YESENIA
VILLACÍS JURADO, ALEXANDRA JAZMÍN
ARAUJO NAVAS, ANDREA LUCÍA
BÉJAR ALBÁN, ANA CRISTINA
SF
PUENTE, JUAN
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Case Report Series: Genetic and clinical characterization of long QT syndrome in admixed Ecuadorian patients and its implications for sudden cardiac death risk
(Frontiers Media SA, 2026-02-12)
PAZ CRUZ, ELIUS ANDRES
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RUIZ POZO, VIVIANA ALEJANDRA
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CADENA ULLAURI, SANTIAGO ANDRÉ
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GUEVARA RAMÍREZ, ALEXANDRA PATRICIA
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TAMAYO TRUJILLO, VICTOR RAFAEL
Long QT syndrome (LQTS) is a hereditary cardiac channelopathy associated with delayed ventricular repolarization and increased risk of life-threatening arrhythmias and sudden cardiac death. We report three Ecuadorian patients with LQTS, each presenting distinct clinical features and carrying pathogenic or likely pathogenic variants in KCNH2 or KCNQ1. Subject A, an 18-year-old woman with exertion-related syncope and a QTc of 520 ms, was diagnosed with LQT2 due to a KCNH2 p.Ala614Val variant. Subject B, a 3-year-old girl with congenital deafness and a QTc of 580 ms, was diagnosed with Jervell and Lange-Nielsen syndrome (JLNS), harboring a homozygous KCNQ1 p.Arg192Cys variant. Subject C, a 44-year-old man with recurrent syncope misdiagnosed as epilepsy and a strong family history of sudden death, was found to carry a KCNH2 p.Val612Met variant and had a QTc of 600 ms. All variants were classified according to ACMG/AMP guidelines and supported by in silico and functional data. Ancestry analysis provided additional genomic context in this admixed population. These cases underscore the clinical utility of integrating ECG findings, genetic testing, and ancestry-informed interpretation to improve diagnostic accuracy and personalize management in patients with inherited arrhythmia syndromes.
Scopus© Citations 1
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Optimizing fish skin scaffolds for regenerative medicine: A comparative study of physical and chemical decellularization techniques
(Elsevier BV, 2026-05)
Esmat Azizipour
;
Hengameh Honarkar
;
Reza Yarahmadi
;
Ahmad Vaez
;
Mehdi Kian
Fish skin scaffolds have great potential as biocompatible materials for skin regeneration, as they contain high levels of collagen and are structurally similar to the mammalian extracellular matrix (ECM). In this study, we compared the efficiency of physical decellularization with chemical decellularization using sodium dodecyl sulphate (SDS), sodium lauryl ether sulfate (SLES), and Triton X-100 at two concentrations (0.5% and 1%) and two time intervals (6 and 12 h). The decellularization efficiency and quality of scaffolds were assessed via histological observations, glycosaminoglycan (GAG) content, MTT assay to evaluate cytocompatibility, scaffold degradation rate, and scanning electron microscopy (SEM) observations. Silicone membrane physical decellularization preserves the integrity of the ECM, retains higher levels of GAG (1.5 µg/mm³) and higher levels of fibroblast viability (p < 0.001) and demonstrates limited degradation (< 20% on day 14) compared to chemical decellularization. Chemical decellularization caused some breakdown of the ECM, particularly treatments at 1%-12h, and was able to retain lower levels of GAG (0.5–0.9 µg/mm³) while degrading more (up to 150%). SEM shows the scaffolds from the physical decellularization treatment had a clearer fibrous structure compared to the variable porosity of the chemical treatment.
Scopus© Citations 1

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