HIDALGO OTTOLENGHI, JOSÉ RICARDO

Preferred name

Main Affiliation

Facultad de Ciencias de la Salud Eugenio Espejo

ORCID

0000-0002-0708-8178

Scopus Author ID

56246158500

Now showing 1 - 10 of 14

Some of the metrics are blocked by your
consent settings
Weighty matters: Unraveling the impact of obesity on colorectal cancer and nutritional interventions
(Elsevier BV, 2025-09-01)
SIMANCAS RACINES, DANIEL ALEJANDRO
;
REYTOR GONZÁLEZ, CLAUDIA MARÍA
;
Evelyn Frias-Toral
;
Christos S. Katsanos
;
HIDALGO OTTOLENGHI, JOSE RICARDO
This narrative review explores the influence of obesity on colorectal cancer, focusing on obesity-related factors, including chronic inflammation, metabolic dysregulation, and gut microbiota imbalance, which collectively create a pro-carcinogenic environment that increases colorectal cancer risk and complicates treatment outcomes. The findings indicate that obesity not only accelerates tumor progression but also presents challenges in colorectal cancer treatment, such as higher rates of surgical complications due to excess adipose tissue and altered pharmacokinetics that can reduce chemotherapy efficacy. Nutritional and lifestyle interventions, particularly weight management and anti-inflammatory nutritional therapies, are highlighted as effective strategies to reduce colorectal cancer risk and support treatment in patients with obesity. The study emphasizes the importance of personalized colorectal cancer treatment approaches for individuals with obesity and calls for public health policies targeting obesity prevention, which could significantly decrease colorectal cancer incidence and healthcare burdens associated with this high-risk population.
Scopus© Citations 19
Some of the metrics are blocked by your
consent settings
Identification of biomedical journals in Spain and Latin America
(Wiley, 2015-07-20)
Xavier Bonfill
;
Dimelza Osorio
;
Margarita Posso
;
Ivan Solà
;
Gabriel Rada
<jats:title>Abstract</jats:title><jats:sec><jats:title>Objectives</jats:title><jats:p>Journals in languages other than English that publish original clinical research are often not well covered in the main biomedical databases and therefore often not included in systematic reviews. This study aimed to identify Spanish language biomedical journals from Spain and Latin America and to describe their main features.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Journals were identified in electronic databases, publishers' catalogues and local registries. Eligibility was determined by assessing data from these sources or the journals' websites, when available.</jats:p></jats:sec><jats:sec><jats:title>Findings</jats:title><jats:p>A total of 2457 journals were initially identified; 1498 met inclusion criteria. Spain (27.3%), Mexico (16.0%), Argentina (15.1%) and Chile (11.9%) had the highest number of journals. Most (85.8%) are currently active; 87.8% have an <jats:styled-content style="fixed-case">ISSN</jats:styled-content>. The median and mean length of publication were 22 and 29 years, respectively. A total of 66.0% were indexed in at least one database; 3.0% had an impact factor in 2012. A total of 845 journals had websites (56.4%), of which 700 (82.8%) were searchable and 681 (80.6%) free of charge.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Most of the identified journals have no impact factor or are not indexed in any of the major databases. The list of identified biomedical journals can be a useful resource when conducting hand searching activities and identifying clinical trials that otherwise would not be retrieved.</jats:p></jats:sec>
Scopus© Citations 16
Some of the metrics are blocked by your
consent settings
Quality of clinical practice guidelines about red blood cell transfusion
(Wiley, 2018-12-03)
SIMANCAS RACINES, DANIEL ALEJANDRO
;
Nadia Montero‐Oleas
;
Robin W.M. Vernooij
;
Ingrid Arevalo‐Rodriguez
;
Paulina Fuentes
<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Red blood cell (RBC) transfusions are essential in health care. The quality of recommendations included in clinical practice guidelines (CPG), regarding this intervention, has not been systematically evaluated. This paper systematically assessed CPGs for RBC‐transfusion, to appraise their methodological quality, to explore changes in quality over time, and to assess the consistency of the hemoglobin threshold (HT) recommendations.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We searched for CPGs that included recommendations of RBC‐transfusion in generic databases, compiler entities, registries, clearinghouses and guideline developers. Three reviewers extracted data on CPGs characteristics and HT recommendations, independently appraised the quality of the studies using AGREE II and resolved disagreements by consensus.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>We examined 16 CPGs. Mean scores (mean ± SD) were: scope and purpose (59.4% ± 19.8%), stakeholder involvement (43.2% ± 22.6%), rigor of development (50% ± 25%), clarity of presentation (74.4% ± 12.6%), applicability (19.4% ± 18.8%), and editorial independence (41% ± 30%). Seven CPGs recommended a restrictive strategy for RBC transfusion; four CPGs gave a guarded statement considering an HT of 7 g/dL, as safe to prescribe an RBC transfusion. Eight CPGs did not provide an HT stating that RBC transfusions should not be prescribed by HT alone.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>Only 3 out of the 16 evaluated CPGs were “recommended” by the independent evaluators. Four domains “stakeholder involvement,” “rigor of development,” applicability,” and “editorial independence” had serious shortcomings. Recommendations about the use of an HT for RBC‐transfusion were heterogeneous among guidelines. Greater efforts are needed to provide high‐quality CPGs in the RBC‐transfusion practice.</jats:p></jats:sec>
Scopus© Citations 21
Some of the metrics are blocked by your
consent settings
Leukodepleted Packed Red Blood Cells Transfusion in Patients Undergoing Major Cardiovascular Surgical Procedure: Systematic Review and Meta-Analysis
(Hindawi Limited, 2019-02-25)
SIMANCAS RACINES, DANIEL ALEJANDRO
;
Ingrid Arevalo-Rodriguez
;
Gerard Urrutia
;
Diana Buitrago-Garcia
;
Solange Núñez-González
<jats:p><jats:italic>Background</jats:italic>. Leukocytes contained in the allogeneic packed red blood cell (PRBC) are the cause of certain adverse reactions associated with blood transfusion. Leukoreduction consists of eliminating leukocytes in all blood products below the established safety levels for any patient type. In this systematic review, we appraise the clinical effectiveness of allogeneic leukodepleted (LD) PRBC transfusion for preventing infections and death in patients undergoing major cardiovascular surgical procedures.<jats:italic>Methods</jats:italic>. We searched randomized controlled trials (RCT), enrolling patients undergoing a major cardiovascular surgical procedure and transfused with LD-PRBC. Data were extracted, and risk of bias was assessed according to Cochrane guidelines. In addition, trial sequential analysis (TSA) was used to assess the need of conducting additional trials. Quality of the evidence was assessed using the GRADE approach.<jats:italic>Results</jats:italic>. Seven studies met the eligibility criteria. Quality of the evidence was rated as moderate for both outcomes. The risk ratio for death from any cause comparing the LD-PRBC versus non-LD-PRBC group was 0.69 (CI 95% = 0.53 to 0.90;<jats:italic>I</jats:italic><jats:sup>2</jats:sup> = 0%). The risk ratio for infection in the same comparison groups was 0.77 (CI 95% = 0.66 to 0.91;<jats:italic>I</jats:italic><jats:sup>2</jats:sup> = 0%). TSA showed a conclusive result in this outcome.<jats:italic>Conclusions</jats:italic>. We found evidence that supports the routine use of leukodepletion in patients undergoing a major cardiovascular surgical procedure requiring PRBC transfusion to prevent death and infection. In the case of infection, the evidence should be considered sufficient and conclusive and hence indicated that further trials would not be required.</jats:p>
Scopus© Citations 22
Some of the metrics are blocked by your
consent settings
El papel de las revisiones sistemáticas. Comentarios
(Ovid Technologies (Wolters Kluwer Health), 2011-11)
HIDALGO OTTOLENGHI, JOSE RICARDO
Scopus© Citations 1
Some of the metrics are blocked by your
consent settings
Exercise training for adult lung transplant recipients
(Wiley, 2021-07-20)
Ruvistay Gutierrez-Arias
;
Maria José Martinez-Zapata
;
Monica C Gaete-Mahn
;
Dimelza Osorio
;
Luis Bustos
Scopus© Citations 18
Some of the metrics are blocked by your
consent settings
Growth references for weight, height, and body mass index for Ecuadorian children and adolescents aged 5-19 years
(Sociedad Argentina de Pediatria, 2020-02-01)
Wilmer Tarupi
;
Yvan Lepage
;
FELIX SALAZAR, MARIA LUISA
;
Claude Monnier
;
Roland Hauspie
Scopus© Citations 5
Some of the metrics are blocked by your
consent settings
Unlocking the potential: very-low-energy ketogenic therapy in obesity-related disorders
(Informa UK Limited, 2025-01-16)
Daniel Simancas-Racines
;
Claudia Reytor-González
;
ZAMBRANO ESPINOSA, ANA KARINA
;
Giuseppe Annunziata
;
Angelo Michele Carella
The Very Low-Energy Ketogenic Therapy (VLEKT) is a structured, multi-phase dietary regimen characterized by a carbohydrate intake of less than 50 g/day and a daily caloric intake of fewer than 800 kcal, which induces ketosis and facilitates significant weight loss. Evidence suggests that this nutritional therapy can improve glycemic control, lipid profiles, and blood pressure, making it a promising option for managing type 2 diabetes (T2D) and reducing cardiovascular risk. These benefits are achieved through reductions in triglycerides and low-density lipoprotein cholesterol (LDL-c), alongside increases in high-density lipoprotein cholesterol (HDL-c). However, the effects of the VLEKT on lipid metabolism remain controversial. The review emphasizes the urgent need for further research to validate the long-term safety and efficacy of the VLEKT. It also highlights the critical role of personalized dietary plans, supervised by healthcare professionals, to optimize health outcomes and address individual patient needs.
Scopus© Citations 13
Some of the metrics are blocked by your
consent settings
Vaccines for the common cold
(Wiley, 2022-12-14)
MONTESINOS GUEVARA, CAMILA MARGARITA
;
Diana Buitrago-Garcia
;
FELIX SALAZAR, MARIA LUISA
;
GUERRA CEVALLOS, CLAUDIA VERONICA
;
Maria José Martinez-Zapata
Scopus© Citations 6
Some of the metrics are blocked by your
consent settings
Cross-sectional study of child and adolescent growth in Ecuador
(Universidad Nacional de La Plata, 2019-06-18)
Wilmer Alexander Tarupi
;
Yvan Lepage
;
Roland Hauspie
;
FELIX SALAZAR, MARIA LUISA
;
Claude Monnier
<jats:p>Child growth is internationally recognized as an important indicator for monitoring health in populations. There exists a wide controversy regarding the use of international growth standards versus local references. This study seeks to construct reference growth curves for school-age Ecuadorian children and adolescents, and to compare them with World Health Organization (WHO) standards, in order to identify the differences and their public health implications. The study authors enrolled 2891 children (1644 girls and 1247 boys) aged 5 to 18 years, from a variety of climatic zones and ethnic groups. LMS method was used to construct Ecuadorian curves for height, weight and Body Mass Index. Comparisons of Ecuadorian and WHO curves were graphically illustrated. U.S children were taller than Ecuadorian children across all age ranges, with larger differences between the two populations in children over 13 years. Consequently, estimates of low height and extremely low height, as well as overweight, obese and undernourished, were significantly different between WHO standards and the Ecuadorian references. Population-specific growth curves may be more adequate for growth monitoring of Ecuadorian children than WHO growth curves. We advocate for the construction of an Ecuadorian growth reference for clinical use based on national population, from conception to maturity, as an accurate instrument for monitoring growth.</jats:p>
Scopus© Citations 6

HIDALGO OTTOLENGHI, JOSÉ RICARDO

Filters

Settings

Sort By

Results per page