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    Identification of genetic biomarkers to predict the response to nutritional therapy in patients with Type 2 Diabetes
    (AG Editor (Argentina), 2025-01-13)
    Domenica Monserrath Robayo Poveda
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    Nathaly Michelle Sánchez Guarnizo
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    Ángel Rafael Balarezo Montaño
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    Carlos Fabian Argotti Zumbana
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    Edison Joshua Jijón Sánchez
    Introduction: The identification of genetic biomarkers to predict the response to nutritional therapy in patients with type 2 diabetes (T2D) has become a promising area to improve the response to therapeutic interventions. In addition, biomarkers are of great help as biological determinants, to study, evaluate and determine Diabetes Mellitus 2. Objective: To analyze the genetic biomarkers associated with the response to nutritional therapy in patients with type 2 diabetes, in order to contribute to the development of personalized strategies that optimize metabolic control and improve the effectiveness of nutritional treatment. Methodology: Systematic review based on PRISMA. 15 studies published between 2018-2023 in databases such as PubMed, Scopus, Scielo, etc. were included. The inclusion criteria were articles on genetic biomarkers, original, systematic review, case studies. Publications prior to 2017, theses and duplicate articles, articles without free access were excluded. Results: The findings highlight the importance of polygenic markers and epigenetic factors, such as DNA methylation, in predicting therapeutic outcomes. Furthermore, the influence of dietary patterns on biomarker expression emphasizes the potential of personalized nutritional strategies in the management of type 2 diabetes. Conclusion: Despite advances in biomarker research, further studies are needed, particularly in Latin American populations, to develop effective interventions tailored to genetic profiles. This study underscores the importance of integrating genetic and environmental factors to improve clinical outcomes in the treatment of type 2 diabetes.
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    El tamal lojano como patrimonio vivo de la gastronomía del Ecuador
    (2025)
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    El patrimonio culinario refleja la tradición y la historia de una región a través de su cocina. La ciudad de Loja, en Ecuador, con sus platos típicos, los cuales han sido elaborados y adaptados a lo largo del tiempo en respuesta a los cambios de consumo. El tamal lojano forma parte esencial de la alimentación de la región, y su preparación facilita la interrelación cultural entre el sector productivo y la sociedad. Esta investigación tiene como objetivo identificar y comprender los procesos y la evolución de los ingredientes que intervienen en la preparación actual y su permanencia en la cocina local, considerándolo un componente importante del patrimonio cultural intangible. La investigación es de tipo cualitativo, utilizando técnicas de observación, entrevistas y revisión bibliográfica. Los resultados obtenidos se analizaron considerando aspectos como la distribución geográfica, los tipos de relleno, la base de la maza y los métodos de cocción.
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    The effect of obesity and body composition on cancer risk: a nutritional perspective
    (AG Editor (Argentina), 2025-01-21)
    Domenica Monserrath Robayo Poveda
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    María José Tuaza Manobanda
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    Emily Valentina Pérez Solis
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    Angelys Milena Villón Andrade
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    Jonathan Alexander Toasa Caisatoa
    Introduction: Obesity is an important risk factor for several types of cancer due to mechanisms such as chronic inflammation and metabolic dysfunctions. In Latin America and Ecuador, obesity affects a large sector of the population, including children, which increases the relevance of preventive measures that promote adequate body composition and healthy eating habits. Objective: To analyze the relationship between obesity, body composition and the risk of cancer, in addition to analyzing how nutritional and physical activity strategies can influence its prevention. Materials and Methods: A narrative review was carried out based on 20 scientific articles extracted from databases such as Scielo, PubMed and Google Scholar, published between 2020 and 2024. Studies on obesity and cancer risk were included, excluding those that did not address this relationship. directly. Results: Excess weight increases the risk of cancer in organs such as the esophagus, liver and breast. Diets such as the Mediterranean diet, rich in antioxidants, reduce this risk, while the consumption of processed meats and alcohol increases it. Discussion: Structured physical activity and personalized nutritional interventions are effective in improving body composition and reducing the incidence of cancer. Conclusion: It is crucial to promote healthy lifestyle habits, combining a balanced diet with physical exercise, to prevent cancer and improve quality of life.