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  4. The role of the Mediterranean diet in prediabetes management and prevention: a review of molecular mechanisms and clinical outcomes
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The role of the Mediterranean diet in prediabetes management and prevention: a review of molecular mechanisms and clinical outcomes

Journal
Food and Agricultural Immunology
ISSN
0954-0105
Date Issued
2024-09-10
Author(s)
RUIZ POZO, VIVIANA ALEJANDRA  
Facultad de Ciencias de la Salud Eugenio Espejo  
GUEVARA RAMIREZ, ALEXANDRA PATRICIA  
Facultad de Ciencias de la Salud Eugenio Espejo  
PAZ CRUZ, ELUIS ANDRES  
Facultad de Ciencias de la Salud Eugenio Espejo  
TAMAYO TRUJILLO, VICTOR RAFAEL  
Facultad de Ciencias de la Salud Eugenio Espejo  
CADENA ULLAURI, SANTIAGO ANDRE  
Facultad de Ciencias de la Salud Eugenio Espejo  
Evelyn Frias-Toral
SIMANCAS RACINES, DANIEL ALEJANDRO  
Facultad de Ciencias de la Salud Eugenio Espejo  
Yekaterina Altuna-Roshkova
Claudia Reytor-González
ZAMBRANO ESPINOSA, ANA KARINA  
Facultad de Ciencias de la Salud Eugenio Espejo  
DOI
https://doi.org/10.1080/09540105.2024.2398042
Abstract
The Mediterranean diet (MedDiet), originating from areas around the Mediterranean Sea, emphasises olive oil, fruits, vegetables, legumes, whole grains, and nuts while limiting red and processed meats. Studies show that higher adherence to the MedDiet reduces mortality risk by 23%.

This diet contains essential nutrients and bioactive compounds important for maintaining good health. Prediabetes, characterised by impaired glucose metabolism and insulin resistance, can progress to type 2 diabetes, which increases the risk of diabetes, cardiovascular events, and mortality. Diet plays a crucial role in type 2 diabetes prevention.

Healthy fats, antioxidants, high fibre, and low glycemic index foods positively affect prediabetes management by improving insulin sensitivity, regulating blood glucose, reducing inflammation, and aiding weight control. This review explores MedDiet’s molecular mechanisms and potential for prediabetes treatment and glycemic control.
Subjects

glycemic control

MedDiet

molecular mechanisms

prediabetes

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