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Endometriosis: Challenges in Clinical Molecular Diagnostics and Treatment
Journal
International Journal of Molecular Sciences
ISSN
1422-0067
Date Issued
2025-04-23
Author(s)
Rosendo-chalma Pedro
Universidad Autónoma de Guerrero, Universidad Nacional Autónoma de México
Erick Nicolás Díaz-Landy
Verónica Antonio-Véjar
Ortiz Tejedor Jonnathan Gerardo
UNIVERSIDAD CATÓLICA DE CUENCA, Universidad Católica de Cuenca
Pontificia Universidad Católica del Ecuador, Universidad UTE
Universidad UTE, Universitat Autònoma de Barcelona Facultat de Medicina
Gabriele Davide Bigoni-Ordóñez
Abstract
Endometriosis is a chronic disease affecting approximately 10% (190 million) of women and girls of reproductive age worldwide. It is associated with a variety of often debilitating symptoms, including severe pelvic pain, pain during intercourse, bowel movements and/or urination, bloating, nausea, fatigue, risk of infertility, as well as depression and anxiety in some cases.
This review summarized the pathogenesis of endometriosis and the criteria for clinical diagnosis, proposed a panel of potential biomarkers for predictive molecular diagnosis, as well as choice of treatments for pain and infertility management.
This review summarized the pathogenesis of endometriosis and the criteria for clinical diagnosis, proposed a panel of potential biomarkers for predictive molecular diagnosis, as well as choice of treatments for pain and infertility management.