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  4. Single-pill combination therapy is the standard of care for hypertension, but it is time for the next step: Implementation
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Single-pill combination therapy is the standard of care for hypertension, but it is time for the next step: Implementation

Journal
Med
ISSN
2666-6340
Date Issued
2024-12
Author(s)
Jose P. Lopez-Lopez
LOPEZ JARAMILLO, JOSÉ PATRICIO  
Facultad de Ciencias de la Salud Eugenio Espejo  
DOI
https://doi.org/10.1016/j.medj.2024.11.010
Abstract
The GMRx2 trial1 in adults with high blood pressure (BP) demonstrated that after 12 weeks, a low-dose single-pill combination of telmisartan, amlodipine, and indapamide significantly reduced BP levels compared to several dual combinations (telmisartan with amlodipine, telmisartan with indapamide, or amlodipine with indapamide).

Adverse events did not differ between the groups.

This novel therapeutic option could improve high BP control
Subjects

Amlodipine

Antihypertensive Agen...

Benzimidazoles

Benzoates

Drug Combinations

Humans

Hypertension

Indapamide

Standard of Care

Telmisarta

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