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SIMANCAS RACINES, DANIEL ALEJANDRO
Preferred name
SIMANCAS RACINES, DANIEL ALEJANDRO
Main Affiliation
SF
ORCID
0000-0002-3641-1501
Scopus Author ID
48561655900
80 results
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Item type:Publication, Trends and space-time analysis of mortality due to diabetes mellitus in Ecuador, 2001-2016(2020) - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Pharmacological interventions for treating heart failure in patients with chagas cardiomyopathy(2012); Nicola, S. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Management and attitudes about IPF (Idiopathic Pulmonary Fibrosis) among physicians from Latin America(Springer Science and Business Media LLC, 2018-01-10)Scopus© Citations 10 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Syntheses of biomedical information: narrative reviews, systematic reviews and emerging formats(Medwave Estudios Limitada, 2018-11-29); Eva MadridScopus© Citations 23 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Molecular pathways and nutrigenomic review of insulin resistance development in gestational diabetes mellitus(Frontiers Media SA, 2023-09-20); ; ; ; <jats:p>Gestational diabetes mellitus is a condition marked by raised blood sugar levels and insulin resistance that usually occurs during the second or third trimester of pregnancy. According to the World Health Organization, hyperglycemia affects 16.9% of pregnancies worldwide. Dietary changes are the primarily alternative treatment for gestational diabetes mellitus. This paper aims to perform an exhaustive overview of the interaction between diet, gene expression, and the metabolic pathways related to insulin resistance. The intake of foods rich in carbohydrates can influence the gene expression of glycolysis, as well as foods rich in fat, can disrupt the beta-oxidation and ketogenesis pathways. Furthermore, vitamins and minerals are related to inflammatory processes regulated by the TLR4/NF-κB and one carbon metabolic pathways. We indicate that diet regulated gene expression of <jats:italic>PPARα</jats:italic>, <jats:italic>NOS</jats:italic>, <jats:italic>CREB3L3</jats:italic>, <jats:italic>IRS</jats:italic>, and <jats:italic>CPT I</jats:italic>, altering cellular physiological mechanisms and thus increasing or decreasing the risk of gestational diabetes. The alteration of gene expression can cause inflammation, inhibition of fatty acid transport, or on the contrary help in the modulation of ketogenesis, improve insulin sensitivity, attenuate the effects of glucotoxicity, and others. Therefore, it is critical to comprehend the metabolic changes of pregnant women with gestational diabetes mellitus, to determine nutrients that help in the prevention and treatment of insulin resistance and its long-term consequences.</jats:p>Scopus© Citations 14 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Effectiveness of postoperative cephalosporins in reducing urinary tract infections and other parameters following transurethral resection of the prostate: a systematic review and meta-analysis(Elsevier BV, 2025-02-01)Scopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Selective removal compared to complete removal for deep carious lesions(Medwave Estudios Limitada, 2020-01-31); Scopus© Citations 6 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Exploring the genetic basis of violence: The impact of Y and X chromosomes(Medwave Estudios Limitada, 2025-07-07); ; ; ; Violence is a pressing global concern, causing more than 475 000 deaths annually and disproportionately affecting women and children. While environmental, genetic, and epigenetic factors contribute to violent behavior, this article focuses on the genetic aspect, particularly the roles of the X and Y chromosomes. The monoamino oxidase A () gene influences neurotransmitter catabolism and is located on the X chromosome. Polymorphisms, such as tandem repeat variants associated with low transcriptional activity, have been linked to aggression, particularly in men, as X chromosome inactivation complicates studies in women. Other variants, including single-nucleotide polymorphisms, have also been associated with violent behavior. Additionally, individuals with fragile X syndrome often exhibit increased aggression patterns. The Y chromosome’s sex-determining region Y gene () plays a pivotal role in male sexual development and behavior. Besides directing testicular formation, is expressed in other tissues, influencing violence by modulating catecholamine release and inhibiting the monoamio oxidasa A. Evolutionary hypotheses suggest that may have adapted to promote male aggression for survival. Despite evidence linking the X and Y chromosomes to violence, conflicting findings highlight the need for further research to fully understand their roles in aggressive behavior. This article focuses on the genetic component, specifically analyzing the bibliographic evidence associating Y and X chromosome genetics to violent behavior. - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Differential impact of coffee quantity and sweetening on body composition parameters and inflammation(Frontiers Media SA, 2025-09-17)Scopus© Citations 1