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Navigating green synthesized metal-based nanoparticles as anti-inflammatory agent – Comprehensive review
(Elsevier BV, 2025-02-10)
Sumanth Hegde
;
Balamuralikrishnan Balasubramanian
;
Ridhika Paul
;
M Jayalakshmi
;
Aatika Nizam
The biosynthesis of nanomaterials is a vast and expanding field of study due to their applications in a variety of fields, particularly the pharmaceutical and biomedical fields. Various synthetic routes, including physical and chemical methods, have been developed in order to generate metal nanoparticles (NPs) with definite shapes and sizes. In this review, focused on the recent advancements in the green synthetic methods for the generation of silver, zinc and copper NPs with simple and eco-friendly approaches and the potential of the biosynthesized metal and metal oxide NPs as alternative and therapeutic agent for the treatment of inflammatory diseases. Inflammation is a body's own defense mechanism that can become chronic inflammation affecting healthy cells. Owning to the size-based advantages of NPs which can mitigate in theses medical conditions and serve as anti-inflammatory drugs. The factors influencing their physicochemical properties, toxicity, biocompatibility and mode of action to formulate an effective nanomedicine in the treatment of inflammation.
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On the horizon of greener pathways to travel into a greener future portal: Green MXenes, environment-friendly synthesis, and their innovative applications
(Elsevier BV, 2024-01)
Ali Mohammad Amani
;
Lobat Tayebi
;
Ehsan Vafa
;
Milad Abbasi
;
Ahmad Vaez
It has been determined that the exceptional characteristics of MXenes are of great interest in a variety of newly developed applications. MXenes, on the other hand, have a number of drawbacks, the most significant of which is that their general manufacturing in large-scale production requires the use of ecologically hazardous and poisonous compounds, as well as a solid-state reaction at high temperature, which is then followed by selective etching. In this regard, the manner in which MXenes are manufactured is critical to determining their final applications. Thus, it is very necessary to develop strategic ways to synthesize MXenes that are safer, greener, more ecologically friendly, and more sustainable in order to put them on the market at a competitive price. It is very necessary to assemble, review, and synthesize the most recent advancements in the green-related innovation of MXenes since there are a rising number of publications on green synthesis involving technological advances and non-toxic substances. Replacing traditional synthesis methods with green MXenes, physically based rapid generation of MAX phases, molten salt process for the green synthesis of MAX phases, nanoparticulate MAX phase based on the sol-gel process, HF etchant replacement with safer chemicals, electrochemical exfoliation, and nanobioagents can result in more environmentally friendly, efficient, and safer MXenes for future environmental, biomedicine, energy saving, catalysis, and sensors. Our primary focus is on the core synthetic procedure, the mechanism, and the overall benefits, with a particular emphasis on the MXene features that have been passed down from these green synthesis approaches. The growing uses green MXenes in the fields of environmental remediation, energy conversion and storage, and biomedicine are discussed in this article. In conclusion, the remaining obstacles and potential benefits of more environmentally friendly MXene production are reviewed.

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