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Author: search.filters.author.Manikantan PappuswamySubject: search.filters.subject.Green synthesis

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    Item type:Publication,
    Navigating green synthesized metal-based nanoparticles as anti-inflammatory agent – Comprehensive review
    (Elsevier BV, 2025-02-10)
    Sumanth Hegde
    ;
    Balamuralikrishnan Balasubramanian
    ;
    Ridhika Paul
    ;
    M Jayalakshmi
    ;
    Aatika Nizam
    The biosynthesis of nanomaterials is a vast and expanding field of study due to their applications in a variety of fields, particularly the pharmaceutical and biomedical fields. Various synthetic routes, including physical and chemical methods, have been developed in order to generate metal nanoparticles (NPs) with definite shapes and sizes. In this review, focused on the recent advancements in the green synthetic methods for the generation of silver, zinc and copper NPs with simple and eco-friendly approaches and the potential of the biosynthesized metal and metal oxide NPs as alternative and therapeutic agent for the treatment of inflammatory diseases. Inflammation is a body's own defense mechanism that can become chronic inflammation affecting healthy cells. Owning to the size-based advantages of NPs which can mitigate in theses medical conditions and serve as anti-inflammatory drugs. The factors influencing their physicochemical properties, toxicity, biocompatibility and mode of action to formulate an effective nanomedicine in the treatment of inflammation.
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    Bioactive nanoparticles derived from marine brown seaweeds and their biological applications: a review
    (Springer Science and Business Media LLC, 2024-06-10)
    Juhi Puthukulangara Jaison
    ;
    Balamuralikrishnan Balasubramanian
    ;
    Jaya Gangwar
    ;
    Manikantan Pappuswamy
    ;
    Arun Meyyazhagan
    The biosynthesis of novel nanoparticles with varied morphologies, which has good implications for their biological capabilities, has attracted increasing attention in the field of nanotechnology. Bioactive compounds present in the extract of fungi, bacteria, plants and algae are responsible for nanoparticle synthesis. In comparison to other biological resources, brown seaweeds can also be useful to convert metal ions to metal nanoparticles because of the presence of richer bioactive chemicals. Carbohydrates, proteins, polysaccharides, vitamins, enzymes, pigments, and secondary metabolites in brown seaweeds act as natural reducing, capping, and stabilizing agents in the nanoparticle’s synthesis. There are around 2000 species of seaweed that dominate marine resources, but only a few have been reported for nanoparticle synthesis. The presence of bioactive chemicals in the biosynthesized metal nanoparticles confers biological activity. The biosynthesized metal and non-metal nanoparticles from brown seaweeds possess different biological activities because of their different physiochemical properties. Compared with terrestrial resources, marine resources are not much explored for nanoparticle synthesis. To confirm their morphology, characterization methods are used, such as absorption spectrophotometer, X-ray diffraction, Fourier transforms infrared spectroscopy, scanning electron microscope, and transmission electron microscopy. This review attempts to include the vital role of brown seaweed in the synthesis of metal and non-metal nanoparticles, as well as the method of synthesis and biological applications such as anticancer, antibacterial, antioxidant, anti-diabetic, and other functions. Graphical abstract: (Figure presented.).