María José Farfán BajañaJuan Carlos ZevallosIvan Chérrez-OjedaGeovanny AlvaradoTiffany GreenBetty KirimiDaniel JaramilloMiguel FelixEmanuel VanegasAlejandra FarfanManuel Cadena-VargasSIMANCAS RACINES, DANIEL ALEJANDRODANIEL ALEJANDROSIMANCAS RACINESMarco Faytong-Haro2024-10-292024-10-292024-08-0510.1186/s12889-024-19561-zhttps://cris.ute.edu.ec/handle/123456789/168<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Compared with conventional cigarettes, electronic cigarettes are less harmful in some studies. However, recent research may indicate the opposite. This study aimed to determine whether e-cigarette use is related to myocardial health in adults in the U.S.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>This study used data from the 2020 Behavioral Risk Factor Surveillance System (BRFSS), a cross-sectional survey of adult US residents aged 18 years or older. We examined whether e-cigarette use was related to myocardial infarction byapplying a logistic regression model to calculate odds ratios (ORs) and 95% confidence intervals (CIs).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The final analytical sample included 198,530 adults in the U.S. Logistic regression indicated that U.S. adults who reported being former and some days of e-cigarette use had 23% and 52% greater odds of ever having an MI, respectively, than did those who reported never using e-cigarettes (OR = 1.23, 95% CI 1.08–1.40, <jats:italic>p</jats:italic> = 0.001; OR = 1.52, 95% CI 1.10–2.09, <jats:italic>p</jats:italic> = 0.010).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>The results suggest that former and someday users of e-cigarettes probably have increased odds of myocardial infarction in adults in the U.S. Further research is needed, including long-term follow-up studies on e-cigarettes, since it is still unknown whether they should be discouraged.</jats:p> </jats:sec>text::journal::journal article